Prilocaine HCl Powder CAS 1786-81-8

Prilocaine hcl powder cas 1786-81-8 is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.

Description

Product introduction

Cas: 1786-81-8

Other names: Prilocaine

MF: C13H21ClN2O

Molecular Weight: 256.77

Perform Standard: USP

Appearance: White crystalline powder, odorless, bitter taste

Loss on drying: ≤0.3%

Residue on ignition: ≤0.1%

Heavy metals: ≤0.002%

Assay: 99.0% ~101.0%

Usage: Prilocaine hcl powder cas 1786-81-8 is a local anesthetic of the amino amide type,it is often used in dentistry. Prilocaine hcl powder cas 1786-81-8 is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.

Application: Prilocaine hcl powder cas 1786-81-8 is the hydrochloride salt form of prilocaine, an intermediate-acting local anesthetic of the amide type chemically related to lidocaine. Prilocaine hcl powder cas 1786-81-8 binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. This leads to a stabilization of the neuronal membrane and inhibits depolarization and results in a reversible blockage of nerve impulse generation and propagation along nerve fibres and subsequent reversible loss of sensation.

Other chemical names: N-(2-methylphenyl)-2-(propylamino)propionamide, Prilocaine N-(2-Methylphenyl)-2-propylamino-propanamide, Astra 1512


Certificate of analysis

Item of Analysis

Standard

Result of Analysis

Description

White crystalline powder, odorless, bitter taste

Complies


Freely soluble in water and in alcohol ,

slightly soluble in chloroform,very slightly soluble in acetone,not soluble in ether

Complies

Melting Point

166~169℃

167.1~168.8℃

Single impurity


≤0.2%

0.01%

Total impurity

≤0.5%

0.02%

Relative Substances A


≤0.01%

0.0039%

Loss on drying


≤ 0.3%

0.04%

Residue on ignition


≤0.1%

0.08%

Heavy metals


≤0.002%

<0.002%

Residual solvents

Should be to match with the standard

Conforms

Assay

99.0% ~101.0%

99.49%


Company Information

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